I’m sure there’ve been many threads like this here, but I haven’t seen them… thought it would be nice to reminisce about the best (and maybe the worst 
games to appear on Sega platforms. My highlights, in whatever order I think of them:
Sonic 1 & 2 on the MS - totally different games to the Megadrive versions. Obviously more limited, but still good.
Spellcaster - great MS platform/RPG which I could never find to buy, but used to rent every weekend for the best part of a year - somehow I’d lose my password virtually every time and not find starting yet again from scratch.
Sonic 2, 3 and Knuckles on the MD (didn’t care for the original too much, but I loved these).
Magic Carpet, Saturn - I’m a die-hard Molyneux addict, and this is one of his best. Some really brutal bugs, but still one of the most enduring games I’ve ever played.
Virtua Fighter 2, Saturn - I’ve barely touched the sequels (not by choice - haven’t had the opportunity), but I still rank this as one of the top fighting games I’ve ever played. I had DC Soul Calibur and it paled by comparison.
Dune II, MD - Still the best version 
Megalomania, MD - another ‘the first RTS’ (probably not, but a great one anyway - and a fantastic intro theme)
Wonderboy III: The Dragon’s Trap, MS - nice blend of RPG and platform… pretty dated, but great in its time and still fun to play.
NBA Jam, MD - never played the sequels but judging by the reviews this was one of the best versions
Jungle Strike, MD - Desert Strike aged much less well (and I never played Urban)
Flashback, MD - one of my all time top games, great story (and one of the only games I’ve ever played with an ending that wasn’t a total letdown)
Virtual On, Saturn - nice if only for the fact that it was a coherent, fun and totally unique kind of game.
Panzer Dragoon Saga, Saturn - surprise 
Panzer Dragoon Zwei, Saturn - I’m not a big shooter fan, but this is a good’n
Guardian Heroes, Saturn - To this day I still alternate seemingly at random between disappointment and elation when I play this, but it still keeps me coming back. And being able to pit a God against ‘village boy’ will never lose it’s appeal >:)
Streets of Rage 3, MD - got criticised a bit for not adding much to 2, but in retrospect I found it a much less repetitive, more imaginative game. Though I prefer Max to Zan…
Battle Master, MD - someone randomly gave this (RPG epic) to me, or I never would’ve played it. Really large for its day, and I don’t know why I love it, but I do.
Cyborg Justice, MD - panned by critics, but I loved sawing opponents limbs off (cue many 'e’s 'armless jokes
Star Control, MD - nowhere near as good as the sequel for single player, but the metamap added a bit to multiplayer which was gone for UQM.
Story of Thor (aka Beyond Oasis), MD - I loved this game to bits… it’s dated a bit, but it’s way better than the Saturn follow-up (a prequel, technically) - even if it only takes 5 hours to complete the 1st run-through Really cleverly done, the way you could summon elementals from virtually any source (ie. Efreet the fire spirit from a dragon’s breath)
Road Rash I-III, MD - I didn’t play RRIII much, but it seemed great. Despite their similarity I found I could play one version to death, move on to the next and somehow still enjoy it. When I got a bunch of MD ROMs a while back, RRII was the one I came back to by far the most.
Streetfighter II: SCE, MD - I got so good at this
Powerstone II, DC - With 3 or more players, this was great. And Capcom pulled off the incredible trick of not making the secret weapons too unbalanced. Even after I unlocked everything I kept coming back (imo far too many games rely on cheap rewards to sustain interest).
San Francisco Rush 2049, DC - Exactly the same comments as Powerstone II apply, basically. Actually, I never finished unlocking everything, but I kept playing for the fun of it and occasionally going on coin collecting drives…
Skies of Arcadia, DC - I hate this kind of game normally. But this had a really nice fusion of different types of battle, spectacular views, a vaguely coherent world and great music.
Resident Evil: Code Veronica, DC - Best RE game I’ve played by a long way. More creepy, marginally less cheesy.
Eternal Champions, MD - not as intricate as SF, but some great imagination behind the characters and techniques.
That’s all I can think of right now
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