Ninja Gaiden 2 - (I imagine you’ve already played, iirc you were a fan of the first game? just treat it as a completely different game, almost as good in it’s own way, but definitely not as good, be ready for lots and lots of PAIN))
Dead Rising - Still something about this one, nothing else has defined “next-gen” any better for me.
Bayonetta - I can despise so much about it, yet I keep going back for more anyway. Sooooo bloody gorgeous…
Portal and Braid - If you want some serious action puzzling with a glorious personality, either fits the bill. Both on XBLA though for Portal the Orange Box might be a better deal, if less “complete” I guess.
Enchanted Arms - I recently returned to this one, and was able to appreciate it for what it is much better. Perhaps it’s greatest crime is how much it can remind me of PDS, and how awful it then seems in comparison. But it doesn’t actually ask to be taken seriously, and if you can get past that there’s a lot to admire.
Death Smiles - On my mind because I recently got it on impulse, NOT disappointed. It’s a phenomenal 2D bullet hell shooter, just about the right balance of chaos vs forgiveness for my old reflexes. lol
Trials HD (XBLA)- I’m including this more because it’s such a cult, and deserves it’s status. Though it’s personality really disagrees with me past a certain point, or I just plain suck at it.
Toy Soldiers (XBLA)- I dunno, I just really enjoy this game, hard to justify, kinda short and sweet. But so well executed on every level.
Radian Games: Joy Joy (Indies)- Just take a look at it, decide for yourself.
Probably forgetting some that I’d include on a different day. Any Halo game or Gears are fully recommended, I’ve actually had more fun with the new franchise this gen I think. Child of Eden & Rez HD both, absolutely. I still haven’t picked up Alan Wake but been meaning to forever, what I have seen and tried of it is very unique and impressive. And if you didn’t try Too Human already… I would almost say don’t. But who knows, some people seem to have made peace with what it is, I certainly can’t.